Immune-profiling of SARS-CoV-2 viremic patients reveals dysregulated innate immune responses

Immune-profiling of SARS-CoV-2 viremic patients reveals dysregulated innate immune responses

SARS-CoV-2 plasma viremia has been associated with severe disease and death in COVID-19. However, the effects of viremia on immune responses in blood cells remain unclear. The current study comprehensively examined transcriptional signatures of PBMCs involving T cells, B cells, NK cells, monocytes,...

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Bibliographic Details
Main Authors: Xiaoming Sun, Ce Gao, Ke Zhao, Yanhui Yang, Yelizaveta Rassadkina, Jesse Fajnzylber, James Regan, Jonathan Z. Li, Mathias Lichterfeld, Xu G. Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVID-19
viremia
RNAseq
interferon stimulated genes
sensing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.984553/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.984553/full

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