Docetaxel-loaded M1 macrophage-derived exosomes for a safe and efficient chemoimmunotherapy of breast cancer

Docetaxel-loaded M1 macrophage-derived exosomes for a safe and efficient chemoimmunotherapy of breast cancer

Abstract The conversion of tumor-promoting M2 macrophage phenotype to tumor-suppressing M1 macrophages is a promising therapeutic approach for cancer treatment. However, the tumor normally provides an abundance of M2 macrophage stimuli, which creates an M2 macrophage-dominant immunosuppressive micro...

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Bibliographic Details
Main Authors: Yongmei Zhao, Yuanlin Zheng, Yan Zhu, Hongyun Li, Hongyan Zhu, Tianqing Liu
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Nanobiotechnology
Subjects:
Exosomes
Macrophage polarization
Tumor immunity
Mitochondrial functions
Breast cancer
Online Access:https://doi.org/10.1186/s12951-022-01526-2

Internet

https://doi.org/10.1186/s12951-022-01526-2

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