Changes in bone turnover markers in patients without bone metastases receiving immune checkpoint inhibitors: An exploratory analysis

Changes in bone turnover markers in patients without bone metastases receiving immune checkpoint inhibitors: An exploratory analysis

Immune checkpoint inhibitors (ICIs) has revolutionized the treatment of different advanced solid tumors, but most patients develop severe immune-related adverse events (irAEs). Although a bi-directional crosstalk between bone and immune systems is widely described, the effect of ICIs on the skeleton...

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Bibliographic Details
Main Authors: Francesco Pantano, Flavia Tramontana, Michele Iuliani, Giulia Leanza, Sonia Simonetti, Alessandra Piccoli, Annalisa Paviglianiti, Alessio Cortellini, Gian Paolo Spinelli, Umile Giuseppe Longo, Rocky Strollo, Bruno Vincenzi, Giuseppe Tonini, Nicola Napoli, Daniele Santini
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Bone Oncology
Subjects:
Type I Collagen C-Terminal Telopeptide (CTX-I)
N-terminal propeptide of type I procollagen (PINP)
Immune checkpoint inhibitors (ICIs)
Bone health
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137422000495

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http://www.sciencedirect.com/science/article/pii/S2212137422000495

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