Filamin A cooperates with the androgen receptor in preventing skeletal muscle senescence

Abstract Aging induces a slow and progressive decrease in muscle mass and function, causing sarcopenia. Androgens control muscle trophism and exert important anabolic functions through the binding to the androgen receptor. Therefore, analysis of the androgen receptor-mediated actions in skeletal mus...

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Bibliographic Details
Main Authors: Marzia Di Donato, Antimo Moretti, Carmela Sorrentino, Giuseppe Toro, Giulia Gentile, Giovanni Iolascon, Gabriella Castoria, Antimo Migliaccio
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01737-y