Engineered extracellular vesicle-delivered TGF-β inhibitor for attenuating osteoarthritis by targeting subchondral bone

Osteoarthritis (OA) is a disease that affects the entire joint. To treat OA, it may be beneficial to inhibit the activity of TGF-β in the subchondral bone. However, delivering drugs to the subchondral bone using conventional methods is challenging. In this study, we developed an extracellular vesicl...

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Bibliographic Details
Main Authors: Zhaopu Jing, Guangyang Zhang, Yuanqing Cai, Jialin Liang, Leifeng Lv, Xiaoqian Dang
Format: Article
Language:English
Published: SAGE Publishing 2024-07-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314241257781