Combined Curcumin and Luteolin Synergistically Inhibit Colon Cancer Associated with Notch1 and TGF-β Signaling Pathways in Cultured Cells and Xenograft Mice

This study aimed to select a combination of curcumin and luteolin, two phytochemicals from food, at lower concentrations with a higher inhibitory effect on colon cancer growth and investigate possible molecular mechanisms of this anti-colon cancer effect. By pairwise combination screening, we identi...

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Bibliographic Details
Main Authors: Rukayat Aromokeye, Hongwei Si
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/12/3001