A human bispecific antibody neutralizes botulinum neurotoxin serotype A

Abstract Botulinum neurotoxin (BoNT) shows high lethality and toxicity, marking it as an important biological threat. The only effective post-exposure therapy is botulinum antitoxin; however, such products have great potential for improvement. To prevent or treat BoNT, monoclonal antibodies (mAbs) a...

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Bibliographic Details
Main Authors: Jiansheng Lu, Yujia Jiang, Jiazheng Guo, Lei Chen, Fujia Liu, Zhiying Li, Xuyang Liu, Peng Du, Yunzhou Yu, Rong Wang, Zhixin Yang
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48008-5