The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract

The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract

Abstract Background Estriol (E3) is a steroid hormone formed only during pregnancy in primates including humans. Although E3 is synthesized at large amounts through a complex pathway involving the fetus and placenta, it is not required for the maintenance of pregnancy and has classically been consid...

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Bibliographic Details
Main Authors: Yuping Zhou, Baoxia Gu, Geraldine Brichant, Jay Prakash Singh, Huan Yang, Hao Chang, Yanding Zhao, Chao Cheng, Zhong-Wu Liu, Myles H. Alderman, Lingeng Lu, Xiaoyong Yang, Xiao-Bing Gao, Hugh S. Taylor
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Biology
Subjects:
Estriol
E3
Epigenetics
DNA methylation
Behavior
Reproduction
Online Access:https://doi.org/10.1186/s12915-022-01293-4

Internet

https://doi.org/10.1186/s12915-022-01293-4

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