Apolipoprotein E and its mimetic peptide suppress Th1 and Th17 responses in experimental autoimmune encephalomyelitis

Apolipoprotein E (apoE) has been detected to possess anti-inflammatory properties that can contribute to protection against experimental autoimmune encephalomyelitis (EAE). However, its impact on Th1 and Th17 responses in EAE is unclear. In this study, we induced EAE in apoE−/− mice and wild-type mi...

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Bibliographic Details
Main Authors: Junjie Wei, Minghua Zheng, Peixiao Liang, Yunfei Wei, Xiaoduan Yin, Yulan Tang, Yimin Xue
Format: Article
Language:English
Published: Elsevier 2013-08-01
Series:Neurobiology of Disease
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Online Access:http://www.sciencedirect.com/science/article/pii/S096999611300123X