CAR-T Regulatory (CAR-Treg) Cells: Engineering and Applications

Regulatory T cells are critical for maintaining immune tolerance. Recent studies have confirmed their therapeutic suppressive potential to modulate immune responses in organ transplant and autoimmune diseases. However, the unknown and nonspecific antigen recognition of polyclonal Tregs has impaired...

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Bibliographic Details
Main Authors: Motahareh Arjomandnejad, Acadia L. Kopec, Allison M. Keeler
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/2/287