Population pharmacokinetic dosimetry model using imaging data to assess variability in pharmacokinetics of 177Lu‐PSMA‐617 in prostate cancer patients

Population pharmacokinetic dosimetry model using imaging data to assess variability in pharmacokinetics of 177Lu‐PSMA‐617 in prostate cancer patients

Abstract Studies to evaluate and optimize [177Lu]Lu‐PSMA treatment focus primarily on individual patient data. A population pharmacokinetic (PK) dosimetry model was developed to explore the potential of using imaging data as input for population PK models and to characterize variability in organ and...

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Bibliographic Details
Main Authors: Hinke Siebinga, Bastiaan M. Privé, Steffie M. B. Peters, James Nagarajah, Thomas P. C. Dorlo, Alwin D. R. Huitema, Berlinda J. deWit‐van der Veen, Jeroen J. M. A. Hendrikx
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12914

Internet

https://doi.org/10.1002/psp4.12914

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