Plasmodium falciparum adapts its investment into replication versus transmission according to the host environment

Plasmodium falciparum adapts its investment into replication versus transmission according to the host environment

The malaria parasite life cycle includes asexual replication in human blood, with a proportion of parasites differentiating to gametocytes required for transmission to mosquitoes. Commitment to differentiate into gametocytes, which is marked by activation of the parasite transcription factor ap2-g,...

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Bibliographic Details
Main Authors: Abdirahman I Abdi, Fiona Achcar, Lauriane Sollelis, João Luiz Silva-Filho, Kioko Mwikali, Michelle Muthui, Shaban Mwangi, Hannah W Kimingi, Benedict Orindi, Cheryl Andisi Kivisi, Manon Alkema, Amrita Chandrasekar, Peter C Bull, Philip Bejon, Katarzyna Modrzynska, Teun Bousema, Matthias Marti
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-03-01
Series:eLife
Subjects:
malaria
transmission
adaptation
host parasite interaction
Online Access:https://elifesciences.org/articles/85140

Internet

https://elifesciences.org/articles/85140

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