Molecular Profiling of Inflammatory Processes in a Mouse Model of IC/BPS: From the Complete Transcriptome to Major Sex-Related Histological Features of the Urinary Bladder

Molecular Profiling of Inflammatory Processes in a Mouse Model of IC/BPS: From the Complete Transcriptome to Major Sex-Related Histological Features of the Urinary Bladder

Animal models are invaluable in the research of the pathophysiology of interstitial cystitis/bladder pain syndrome (IC/BPS), a chronic aseptic urinary bladder disease of unknown etiology that primarily affects women. Here, a mouse model of IC/BPS was induced with multiple low-dose cyclophosphamide (...

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Bibliographic Details
Main Authors: Dominika Peskar, Tadeja Kuret, Katja Lakota, Andreja Erman
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
interstitial cystitis/bladder pain syndrome
inflammation
RNA sequencing
animal model
cyclophosphamide
Online Access:https://www.mdpi.com/1422-0067/24/6/5758

Internet

https://www.mdpi.com/1422-0067/24/6/5758

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