Ripa-56 protects retinal ganglion cells in glutamate-induced retinal excitotoxic model of glaucoma

Ripa-56 protects retinal ganglion cells in glutamate-induced retinal excitotoxic model of glaucoma

Abstract Glaucoma is a prevalent cause of blindness globally, characterized by the progressive degeneration of retinal ganglion cells (RGCs). Among various factors, glutamate excitotoxicity stands out as a significant contributor of RGCs loss in glaucoma. Our study focused on Ripa-56 and its protect...

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Bibliographic Details
Main Authors: Lemeng Feng, Shirui Dai, Cheng Zhang, Wulong Zhang, Weiming Zhu, Chao Wang, Ye He, Weitao Song
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Subjects:
Glaucoma
Glutamate
Ferroptosis
Apoptosis
Necroptosis
Ripa-56
Online Access:https://doi.org/10.1038/s41598-024-54075-z

Internet

https://doi.org/10.1038/s41598-024-54075-z

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