Minimum important difference is minimally important in sample size calculations

Abstract Performing a sample size calculation for a randomized controlled trial requires specifying an assumed benefit (that is, the mean improvement in outcomes due to the intervention) and a target power. There is a widespread belief that judgments about the minimum important difference should be...

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Bibliographic Details
Main Author: Hubert Wong
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-023-07092-8