Praeruptorin B inhibits osteoclastogenesis by targeting GSTP1 and impacting on the S-glutathionylation of IKKβ

Praeruptorin B inhibits osteoclastogenesis by targeting GSTP1 and impacting on the S-glutathionylation of IKKβ

Osteoporosis a common disease in postmenopausal women which contains significant impact on the living quality of women. With the aging of the population, the number of patients suffer from osteoporosis has shown a significant increase. Given the limitations of clinical drugs for the treatment of ost...

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Bibliographic Details
Main Authors: Kebin Xu, Ziyi Chen, Jialong Hou, Chenlin Dong, Chengge Shi, Linglin Gao, Zhixian Huang, Ge Shen, Te Wang, Yan Zhou
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Praeruptorin B
GSTP1
Nuclear factor κB
Receptor activator of nuclear factor κB ligand
Osteoclastogenesis
Osteoporosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222009180

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http://www.sciencedirect.com/science/article/pii/S0753332222009180

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