Exploring the mechanism of aloe-emodin in the treatment of liver cancer through network pharmacology and cell experiments

Exploring the mechanism of aloe-emodin in the treatment of liver cancer through network pharmacology and cell experiments

Objective: Aloe-emodin (AE) is an anthraquinone compound extracted from the rhizome of the natural plant rhubarb. Initially, it was shown that AE exerts an anti-inflammatory effect. Further studies revealed its antitumor activity against various types of cancer. However, the mechanisms underlying th...

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Bibliographic Details
Main Authors: Mingyang Zhu, Qingmin He, Yanan Wang, Liying Duan, Kang Rong, Yingying Wu, Ye Ding, Yang Mi, Xiaoyang Ge, Xiaocui Yang, Yong Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pharmacology
Subjects:
molecular docking
network pharmacology
aloe-emodin
hepatocellular carcinoma
molecular mechanism
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1238841/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1238841/full

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