Structural analysis of the C-terminal region (modules 18-20) of complement regulator factor H (FH).

Structural analysis of the C-terminal region (modules 18-20) of complement regulator factor H (FH).

Factor H (FH) is a soluble regulator of the human complement system affording protection to host tissues. It selectively inhibits amplification of C3b, the activation-specific fragment of the abundant complement component C3, in fluid phase and on self-surfaces and accelerates the decay of the alter...

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Bibliografiske detaljer
Main Authors: Hugh P Morgan, Haydyn D T Mertens, Mara Guariento, Christoph Q Schmidt, Dinesh C Soares, Dmitri I Svergun, Andrew P Herbert, Paul N Barlow, Jonathan P Hannan
Format: Article
Sprog:English
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3289644?pdf=render

Internet

http://europepmc.org/articles/PMC3289644?pdf=render

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