NPM 1 Mutations in AML—The Landscape in 2023
Acute myeloid leukemia (AML) represents 80% of acute leukemia in adults and is characterized by clonal expansion of hematopoietic stem cells secondary to genomic mutations, rendering a selective growth advantage to the mutant clones. NPM1<i>mut</i> is found in around 30% of AML and clini...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-02-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/15/4/1177 |