NPM 1 Mutations in AML—The Landscape in 2023

Acute myeloid leukemia (AML) represents 80% of acute leukemia in adults and is characterized by clonal expansion of hematopoietic stem cells secondary to genomic mutations, rendering a selective growth advantage to the mutant clones. NPM1<i>mut</i> is found in around 30% of AML and clini...

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Bibliographic Details
Main Authors: Naman Sharma, Jane L. Liesveld
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/4/1177