GFOGER Peptide Modifies the Protein Content of Extracellular Vesicles and Inhibits Vascular Calcification

GFOGER Peptide Modifies the Protein Content of Extracellular Vesicles and Inhibits Vascular Calcification

ObjectiveVascular calcification (VC) is an active process during which vascular smooth muscle cells (VSMCs) undergo an osteogenic switch and release extracellular vesicles (EVs). In turn, the EVs serve as calcification foci via interaction with type 1 collagen (COL1). We recently showed that a speci...

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Bibliographic Details
Main Authors: Ali Mansour, Walaa Darwiche, Linda Yaker, Sophie Da Nascimento, Cathy Gomila, Claire Rossi, Vincent Jung, Pascal Sonnet, Saïd Kamel, Ida Chiara Guerrera, Agnès Boullier, Jérôme Ausseil
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
vascular calcification
type I collagen
extracellular vesicle
oligogalacturonic acid
GFOGER sequence
osteogenic switch
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.589761/full

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https://www.frontiersin.org/articles/10.3389/fcell.2020.589761/full

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