The oral commensal Streptococcus mitis shows a mixed memory Th cell signature that is similar to and cross-reactive with Streptococcus pneumoniae.

BACKGROUND: Carriage of and infection with Streptococcus pneumoniae is known to predominantly induce T helper 17 (Th17) responses in humans, but the types of Th cells showing reactivity towards commensal streptococci with low pathogenic potential, such as the oral commensals S. mitis and S. salivari...

Full description

Bibliographic Details
Main Authors: Stian André Engen, Håkon Valen Rukke, Simone Becattini, David Jarrossay, Inger Johanne Blix, Fernanda Cristina Petersen, Federica Sallusto, Karl Schenck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4131883?pdf=render