Beneficial effects of Cyclosporine A in combination with Nortriptyline on germ cell-specific apoptosis, oxidative stress and epididymal sperm qualities following testicular ischemia/reperfusion in rats: a comparative study
Abstract Background Testicular torsion is a pathological condition which needs emergency surgical intervention. However, after surgical reperfusion, oxidative stress factors cause to germ cell apoptosis. The study was planned to evaluate the efficacy of simultaneous use of Cyclosporine A (CsA) and N...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-08-01
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Series: | BMC Pharmacology and Toxicology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40360-022-00601-6 |