Beneficial effects of Cyclosporine A in combination with Nortriptyline on germ cell-specific apoptosis, oxidative stress and epididymal sperm qualities following testicular ischemia/reperfusion in rats: a comparative study

Beneficial effects of Cyclosporine A in combination with Nortriptyline on germ cell-specific apoptosis, oxidative stress and epididymal sperm qualities following testicular ischemia/reperfusion in rats: a comparative study

Abstract Background Testicular torsion is a pathological condition which needs emergency surgical intervention. However, after surgical reperfusion, oxidative stress factors cause to germ cell apoptosis. The study was planned to evaluate the efficacy of simultaneous use of Cyclosporine A (CsA) and N...

Full description

Bibliographic Details
Main Authors: Iraj Yazdani, Raheleh Majdani, Morteza Ghasemnejad-berenji, Ahmad Reza Dehpour
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Pharmacology and Toxicology
Subjects:
Apoptosis
Cyclosporine A
Nortriptyline
Oxidative stress
Sperm
Testicular T/D
Online Access:https://doi.org/10.1186/s40360-022-00601-6

Similar Items

Similar Items