Influence of route of administration and lipidation of apolipoprotein A-I peptide on pharmacokinetics and cholesterol mobilization

Influence of route of administration and lipidation of apolipoprotein A-I peptide on pharmacokinetics and cholesterol mobilization

apoA-I, apoA-I mimetic peptides, and their lipid complexes or reconstituted high-density lipoprotein (HDL) have been studied as treatments for various pathologies. However, consensus is lacking about the best method for administration, by intravenous (IV) or intraperitoneal (IP) routes, and formulat...

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Bibliografische gegevens
Hoofdauteurs: Jie Tang, Dan Li, Lindsey Drake, Wenmin Yuan, Sara Deschaine, Emily E. Morin, Rose Ackermann, Karl Olsen, David E. Smith, Anna Schwendeman
Formaat: Artikel
Taal:English
Gepubliceerd in: Elsevier 2017-01-01
Reeks:Journal of Lipid Research
Onderwerpen:
HDL
lipoproteins/metabolism
apolipoprotein A-I mimetic peptides
lipoprotein remodeling
PK-PD modeling
Online toegang:http://www.sciencedirect.com/science/article/pii/S0022227520314413

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http://www.sciencedirect.com/science/article/pii/S0022227520314413

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