Transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertension

Transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertension

Summary: Persistent liver injury triggers a fibrogenic program that causes pathologic remodeling of the hepatic microenvironment (i.e., liver fibrosis) and portal hypertension. The dynamics of gene regulation during liver disease progression and early regression remain understudied. Here, we generat...

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Bibliographic Details
Main Authors:	Oleksandr Petrenko, Philipp Königshofer, Ksenia Brusilovskaya, Benedikt S. Hofer, Katharina Bareiner, Benedikt Simbrunner, Frank Jühling, Thomas F. Baumert, Joachim Lupberger, Michael Trauner, Stefan G. Kauschke, Larissa Pfisterer, Eric Simon, André F. Rendeiro, Laura P.M.H. de Rooij, Philipp Schwabl, Thomas Reiberger
Format:	Article
Language:	English
Published:	Elsevier 2024-03-01
Series:	iScience
Subjects:	Disease Fibrosis Integrative aspects of cell biology Model organism Transcriptomics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004224005224

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