Transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertension

Transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertension

Summary: Persistent liver injury triggers a fibrogenic program that causes pathologic remodeling of the hepatic microenvironment (i.e., liver fibrosis) and portal hypertension. The dynamics of gene regulation during liver disease progression and early regression remain understudied. Here, we generat...

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Main Authors: Oleksandr Petrenko, Philipp Königshofer, Ksenia Brusilovskaya, Benedikt S. Hofer, Katharina Bareiner, Benedikt Simbrunner, Frank Jühling, Thomas F. Baumert, Joachim Lupberger, Michael Trauner, Stefan G. Kauschke, Larissa Pfisterer, Eric Simon, André F. Rendeiro, Laura P.M.H. de Rooij, Philipp Schwabl, Thomas Reiberger
格式: 文件
语言:English
出版: Elsevier 2024-03-01
丛编:iScience
主题:
Disease
Fibrosis
Integrative aspects of cell biology
Model organism
Transcriptomics
在线阅读:http://www.sciencedirect.com/science/article/pii/S2589004224005224

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