Association of <i>TP53</i> Alteration with Tissue Specificity and Patient Outcome of <i>IDH1</i>-Mutant Glioma

Since the initial discovery of recurrent isocitrate dehydrogenase 1 (<i>IDH1)</i> mutations at Arg132 in glioma, <i>IDH1</i> hotspot mutations have been identified in cholangiocarcinoma, chondrosarcoma, leukemia, and various other types of cancer of sporadic incidence. Studie...

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Bibliographic Details
Main Authors: Balazs Murnyak, L. Eric Huang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/8/2116