The genomic stability regulator PTIP is required for proper chromosome segregation in mitosis

The genomic stability regulator PTIP is required for proper chromosome segregation in mitosis

Abstract Background The Pax transcription activation domain-interacting protein (PTIP) is a nuclear protein that is an essential component of H3K4 methylation for gene activation in vascular, kidney, B cell, and adipocyte development. Furthermore, it plays a key role in genomic stability in higher e...

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Bibliographic Details
Main Authors: Fengxia Zhang, Mingxuan Wei, Haoran Chen, Liting Ji, Yan Nie, Jungseog Kang
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Cell Division
Subjects:
Chromosome segregation
Mitosis
Genetic instability
Centrosome
DNA damage
PTIP
Online Access:https://doi.org/10.1186/s13008-022-00081-4

Internet

https://doi.org/10.1186/s13008-022-00081-4

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