Polyunsaturated Fatty Acids Attenuate Diet Induced Obesity and Insulin Resistance, Modulating Mitochondrial Respiratory Uncoupling in Rat Skeletal Muscle.

OBJECTIVES:Omega (ω)-3 polyunsaturated fatty acids (PUFA) are dietary compounds able to attenuate insulin resistance. Anyway, the precise actions of ω-3PUFAs in skeletal muscle are overlooked. We hypothesized that PUFAs, modulating mitochondrial function and efficiency, would ameliorate pro-inflamma...

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Main Authors: Gina Cavaliere, Giovanna Trinchese, Paolo Bergamo, Chiara De Filippo, Giuseppina Mattace Raso, Giorgio Gifuni, Rosalba Putti, Bottu Heleena Moni, Roberto Berni Canani, Rosaria Meli, Maria Pina Mollica
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4762694?pdf=render