Responsiveness to basement membrane extract as a possible trait for tumorigenicity characterization
Immortalized cell lines used to produce vaccines are expected to be described in terms of their tumorigenicity. However, current in vivo tumorigenicity assays can be time-consuming and results can be equivocal, especially for weakly tumorigenic cells. Basement membrane extract (BME) derived from the...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-04-01
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Series: | Vaccine: X |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590136219300014 |