Parkin deficiency exacerbates fasting-induced skeletal muscle wasting in mice
Abstract Parkinson’s Disease (PD) is a chronic and progressive neurodegenerative disease manifesting itself with tremors, muscle stiffness, bradykinesia, dementia, and depression. Mutations of mitochondrial E3 ligase, PARKIN, have been associated with juvenile PD. Previous studies have characterized...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
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Series: | npj Parkinson's Disease |
Online Access: | https://doi.org/10.1038/s41531-022-00419-3 |