Generation and metabolomic characterization of functional ductal organoids with biliary tree networks in decellularized liver scaffolds

Generation and metabolomic characterization of functional ductal organoids with biliary tree networks in decellularized liver scaffolds

Developing functional ductal organoids (FDOs) is essential for liver regenerative medicine. We aimed to construct FDOs with biliary tree networks in rat decellularized liver scaffolds (DLSs) with primary cholangiocytes isolated from mouse bile ducts. The developed FDOs were dynamically characterized...

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Bibliographic Details
Main Authors: Jiaxian Chen, Shiwen Ma, Hui Yang, Xi Liang, Heng Yao, Beibei Guo, Deying Chen, Jing Jiang, Dongyan Shi, Jiaojiao Xin, Keke Ren, Xingping Zhou, Yun Li, Lei Geng, Jun Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-08-01
Series:Bioactive Materials
Subjects:
Cholangiocyte
Decellularized scaffold
Ductal organoid
Extracellular matrix
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2300097X

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http://www.sciencedirect.com/science/article/pii/S2452199X2300097X

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