CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90

CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90

<p>Abstract</p> <p>Background</p> <p>HIV-1 transcription is activated by the viral Tat protein that recruits host positive transcription elongation factor-b (P-TEFb) containing CDK9/cyclin T1 to the HIV-1 promoter. P-TEFb in the cells exists as a lower molecular weight...

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Bibliographic Details
Main Authors: Breuer Denitra, Kotelkin Alexander, Ammosova Tatiana, Kumari Namita, Ivanov Andrey, Ilatovskiy Andrey V, Beullens Monique, Roane Philip R, Bollen Mathieu, Petukhov Michael G, Kashanchi Fatah, Nekhai Sergei
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/9/1/94

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http://www.retrovirology.com/content/9/1/94

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