DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma

Summary: Although melanoma-associated antigen A3 and A6 (MAGEA3/6)-specific tumor vaccines have shown antitumor effects in melanoma and non-small cell lung cancer (NSCLC), many cancers do not respond because MAGEA3 can promote cancer without triggering an immune response. Here, we identified DUB3 as...

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Bibliographic Details
Main Authors: Yuanhong Chen, Feng Gao, Yan He, Meijun Liu, Yuan Quan, Peijing Zhang
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224004024