A Model for NAD(P)H: Quinoneoxidoreductase 1 (NQO1) Targeted Individualized Cancer Chemotherapy
NQO1 (NAD(P)H:quinoneoxidoreductase 1) is a reductive enzyme that is an important activator of bioreductive antitumor agents. NQO1 activity varies in individual tumors but is generally higher in tumor cells than in normal cells. NQO1 has been used as a target for tumor specific drug development. We...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AboutScience Srl
2009-01-01
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| Series: | Drug Target Insights |
| Online Access: | https://doi.org/10.4137/DTI.S1146 |