Selective treatment pressure in colon cancer drives the molecular profile of resistant circulating tumor cell clones

Selective treatment pressure in colon cancer drives the molecular profile of resistant circulating tumor cell clones

Abstract The characterization of circulating tumor cells (CTCs) holds promises for precision medicine because these cells are an important clinical indicator of treatment efficacy. We established the first and still only nine permanent colon CTC lines from peripheral blood samples of a patient with...

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Bibliographic Details
Main Authors: Laure Cayrefourcq, Frédéric Thomas, Thibault Mazard, Eric Assenat, Said Assou, Catherine Alix-Panabières
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Molecular Cancer
Subjects:
Circulating tumor cells
Gene expression
Clonal evolution
Colon cancer
CDA
ALDOB
Online Access:https://doi.org/10.1186/s12943-021-01326-6

Internet

https://doi.org/10.1186/s12943-021-01326-6

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