The ER membrane complex (EMC) can functionally replace the Oxa1 insertase in mitochondria

Two multisubunit protein complexes for membrane protein insertion were recently identified in the endoplasmic reticulum (ER): the guided entry of tail anchor proteins (GET) complex and ER membrane complex (EMC). The structures of both of their hydrophobic core subunits, which are required for the in...

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Bibliographic Details
Main Authors: Büsra Güngör, Tamara Flohr, Sriram G. Garg, Johannes M. Herrmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887752/?tool=EBI