Effects of exogenous deoxyribonuclease I in collagen antibody-induced arthritis

Effects of exogenous deoxyribonuclease I in collagen antibody-induced arthritis

Abstract Background Rheumatoid arthritis (RA) is associated with a high concentration of extracellular DNA (ecDNA). This could be a consequence of the inflammation, but the ecDNA could also be involved in the unknown etiopathogenesis of RA. Clearance of ecDNA is hypothesized to prevent the developme...

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Bibliographic Details
Main Authors: Kristína Macáková, Veronika Borbélyová, Mária Tekeľová, Jakub Janko, Michal Pastorek, Richard Hokša, Norbert Moravanský, Emöke Šteňová, Barbora Vlková, Peter Celec
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Journal of Inflammation
Subjects:
Cell-free DNA
Deoxyribonuclease
Autoimmune disease
Chronic inflammation
Online Access:https://doi.org/10.1186/s12950-024-00403-z

Internet

https://doi.org/10.1186/s12950-024-00403-z

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