Genetic Variation in CCL18 Gene Influences CCL18 Expression and Correlates with Survival in Idiopathic Pulmonary Fibrosis: Part A

Genetic Variation in CCL18 Gene Influences CCL18 Expression and Correlates with Survival in Idiopathic Pulmonary Fibrosis: Part A

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic disease, characterized by fibroblast proliferation and extracellular matrix deposition. CC-chemokine ligand 18 (CCL18) upregulates the production of collagen by lung fibroblasts and is associated with mortality. This study was designed to...

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Bibliographic Details
Main Authors: Ivo A. Wiertz, Sofia A. Moll, Benjamin Seeliger, Nicole P. Barlo, Joanne J. van der Vis, Nicoline M. Korthagen, Ger T. Rijkers, Henk J.T. Ruven, Jan C. Grutters, Antje Prasse, Coline H.M. van Moorsel
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Journal of Clinical Medicine
Subjects:
idiopathic pulmonary fibrosis
chemokine
CCL18
single nucleotide polymorphism
survival
Online Access:https://www.mdpi.com/2077-0383/9/6/1940

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https://www.mdpi.com/2077-0383/9/6/1940

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