<sup>225</sup>Ac-iPSMA-RGD for Alpha-Therapy Dual Targeting of Stromal/Tumor Cell PSMA and Integrins

<sup>225</sup>Ac-iPSMA-RGD for Alpha-Therapy Dual Targeting of Stromal/Tumor Cell PSMA and Integrins

Prostate-specific membrane antigens (PSMAs) are frequently overexpressed in both tumor stromal endothelial cells and malignant cells (stromal/tumor cells) of various cancers. The RGD (Arg-Gly-Asp) peptide sequence can specifically detect integrins involved in tumor angiogenesis. This study aimed to...

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Bibliographic Details
Main Authors: Blanca Ocampo-García, Pedro Cruz-Nova, Nallely Jiménez-Mancilla, Myrna Luna-Gutiérrez, Rigoberto Oros-Pantoja, Nancy Lara-Almazán, Diana Pérez-Velasco, Clara Santos-Cuevas, Guillermina Ferro-Flores
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
actinium-225
PSMA
RGD
dual-targeting
alpha-therapy
PSMA-RGD
Online Access:https://www.mdpi.com/1422-0067/24/23/16553

Internet

https://www.mdpi.com/1422-0067/24/23/16553

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