Renal denervation decreases blood pressure and renal tyrosine hydroxylase but does not augment the effect of hypotensive drugs

The effect of renal denervation on the efficacy of antihypertensive drugs has not yet been elucidated. Twenty-week-old spontaneously hypertensive rats were treated with metoprolol, losartan, indapamide, or saline (controls) and assigned to renal denervation or a sham procedure. Acute hemodynamic mea...

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Bibliographic Details
Main Authors: Janusz Skrzypecki, Maciej Gawlak, Tomasz Huc, Paweł Szulczyk, Marcin Ufnal
Format: Article
Language:English
Published: Taylor & Francis Group 2017-04-01
Series:Clinical and Experimental Hypertension
Subjects:
Online Access:http://dx.doi.org/10.1080/10641963.2016.1267191