IKK2/NF-κB Activation in Astrocytes Reduces amyloid β Deposition: A Process Associated with Specific Microglia Polarization

IKK2/NF-κB Activation in Astrocytes Reduces amyloid β Deposition: A Process Associated with Specific Microglia Polarization

Alzheimer’s disease (AD) is a common neurodegenerative disease that is accompanied by pronounced neuroinflammatory responses mainly characterized by marked microgliosis and astrogliosis. However, it remains open as to how different aspects of astrocytic and microglial activation affect disease progr...

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Bibliographic Details
Main Authors: Shu Yang, Alexander Magnutzki, Najwa Ouali Alami, Michael Lattke, Tabea Melissa Hein, Judith Stefanie Scheller, Carsten Kröger, Franz Oswald, Deniz Yilmazer-Hanke, Thomas Wirth, Bernd Baumann
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
neuroinflammation
Alzheimer’s disease
NF-κB
IKK
astrocytes
astrogliosis
Online Access:https://www.mdpi.com/2073-4409/10/10/2669

Internet

https://www.mdpi.com/2073-4409/10/10/2669

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