Recruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase II.

Recruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase II.

Messenger RNA (mRNA) synthesis and export are tightly linked, but the molecular mechanisms of this coupling are largely unknown. In Saccharomyces cerevisiae, the conserved TREX complex couples transcription to mRNA export and mediates mRNP formation. Here, we show that TREX is recruited to the trans...

Full description

Bibliographic Details
Main Authors: Dominik M Meinel, Cornelia Burkert-Kautzsch, Anja Kieser, Eoghan O'Duibhir, Matthias Siebert, Andreas Mayer, Patrick Cramer, Johannes Söding, Frank C P Holstege, Katja Sträßer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3828145?pdf=render

Internet

http://europepmc.org/articles/PMC3828145?pdf=render

Similar Items