RIP-seq reveals LINE-1 ORF1p association with p-body enriched mRNAs

Abstract Background Long INterspersed Element-1 (LINE-1) is an autonomous retroelement able to “copy-and-paste” itself into new loci of the host genome through a process called retrotransposition. The LINE-1 bicistronic mRNA codes for two proteins, ORF1p, a nucleic acid chaperone, and ORF2p, a prote...

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Bibliographic Details
Main Authors: Erica M. Briggs, Wilson McKerrow, Paolo Mita, Jef D. Boeke, Susan K. Logan, David Fenyö
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Mobile DNA
Subjects:
Online Access:https://doi.org/10.1186/s13100-021-00233-3