Evidence of Neutralizing and Non-Neutralizing Anti-Glucosaminidase Antibodies in Patients With S. Aureus Osteomyelitis and Their Association With Clinical Outcome Following Surgery in a Clinical Pilot

Evidence of Neutralizing and Non-Neutralizing Anti-Glucosaminidase Antibodies in Patients With S. Aureus Osteomyelitis and Their Association With Clinical Outcome Following Surgery in a Clinical Pilot

Staphylococcus aureus osteomyelitis remains a very challenging condition; recent clinical studies have shown infection control rates following surgery/antibiotics to be ~60%. Additionally, prior efforts to produce an effective S. aureus vaccine have failed, in part due to lack of knowledge of protec...

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Bibliographic Details
Main Authors: Shardulendra Prasad Sherchand, Rajan P. Adhikari, Gowrishankar Muthukrishnan, Tulasikumari Kanipakala, John R. Owen, Chao Xie, M. Javad Aman, Richard A. Proctor, Edward M. Schwarz, Stephen L. Kates
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Staphylococcus aureus
osteomyelitis
glucosaminidase
antibodies
immunoassay
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.876898/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.876898/full

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