Large-conductance Ca2+-activated potassium channels are potently involved in the inverse neurovascular response to spreading depolarization

Large-conductance Ca2+-activated potassium channels are potently involved in the inverse neurovascular response to spreading depolarization

Recurrent spreading depolarizations occur in the cerebral cortex from minutes up to weeks following acute brain injury. Clinical evidence suggests that the immediate reduction of cerebral blood flow in response to spreading depolarization importantly contributes to lesion progression as the wave pro...

Full description

Bibliographic Details
Main Authors: Ákos Menyhárt, Attila E. Farkas, Dániel P. Varga, Rita Frank, Réka Tóth, Armand R. Bálint, Péter Makra, Jens P. Dreier, Ferenc Bari, István A. Krizbai, Eszter Farkas
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Neurobiology of Disease
Subjects:
Calcium channels
Cerebral arteriole
Cerebral blood flow
Potassium
Potassium channels
Neurovascular coupling
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611830322X

Internet

http://www.sciencedirect.com/science/article/pii/S096999611830322X

Similar Items