The SCRIPT trial: study protocol for a randomised controlled trial of a polygenic risk score to tailor colorectal cancer screening in primary care

The SCRIPT trial: study protocol for a randomised controlled trial of a polygenic risk score to tailor colorectal cancer screening in primary care

Abstract Background Polygenic risk scores (PRSs) can predict the risk of colorectal cancer (CRC) and target screening more precisely than current guidelines using age and family history alone. Primary care, as a far-reaching point of healthcare and routine provider of cancer screening and risk infor...

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Bibliographic Details
Main Authors: Sibel Saya, Lucy Boyd, Patty Chondros, Mairead McNamara, Michelle King, Shakira Milton, Richard De Abreu Lourenco, Malcolm Clark, George Fishman, Julie Marker, Cheri Ostroff, Richard Allman, Fiona M. Walter, Daniel Buchanan, Ingrid Winship, Jennifer McIntosh, Finlay Macrae, Mark Jenkins, Jon Emery
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Trials
Subjects:
Colorectal cancer
Cancer screening
Risk-stratified screening
Primary care
Faecal occult Blood test
General practice
Online Access:https://doi.org/10.1186/s13063-022-06734-7

Internet

https://doi.org/10.1186/s13063-022-06734-7

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