RaPID: ultra-fast, powerful, and accurate detection of segments identical by descent (IBD) in biobank-scale cohorts

RaPID: ultra-fast, powerful, and accurate detection of segments identical by descent (IBD) in biobank-scale cohorts

Abstract While genetic relatedness, usually manifested as segments identical by descent (IBD), is ubiquitous in modern large biobanks, current IBD detection methods are not efficient at such a scale. Here, we describe an efficient method, RaPID, for detecting IBD segments in a panel with phased hapl...

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Bibliographic Details
Main Authors: Ardalan Naseri, Xiaoming Liu, Kecong Tang, Shaojie Zhang, Degui Zhi
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Genome Biology
Subjects:
Identity by descent
IBD
PBWT
Random projection
UK Biobank
Online Access:http://link.springer.com/article/10.1186/s13059-019-1754-8

Internet

http://link.springer.com/article/10.1186/s13059-019-1754-8

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