Cell Populations Expressing Stemness-Associated Markers in Lung Adenocarcinoma

Cell Populations Expressing Stemness-Associated Markers in Lung Adenocarcinoma

The stemness-associated markers OCT4, NANOG, SOX2, KLF4 and c-MYC are expressed in numerous cancer types suggesting the presence of cancer stem cells (CSCs). Immunohistochemical (IHC) staining performed on 12 lung adenocarcinoma (LA) tissue samples showed protein expression of OCT4, NANOG, SOX2, KLF...

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Bibliographic Details
Main Authors: Claudia Paterson, Ethan J. Kilmister, Helen D. Brasch, Nicholas Bockett, Josie Patel, Erin Paterson, Gordon Purdie, Sean Galvin, Paul F. Davis, Tinte Itinteang, Swee T. Tan
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Life
Subjects:
lung adenocarcinoma
stemness-associated markers
induced pluripotent stem cells
embryonic stem cells
cancer stem cells
treatment resistance
Online Access:https://www.mdpi.com/2075-1729/11/10/1106

Internet

https://www.mdpi.com/2075-1729/11/10/1106

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