Phenotypic changes associated with Colistin resistance due to Lipopolysaccharide loss in Acinetobacter baumannii

Phenotypic changes associated with Colistin resistance due to Lipopolysaccharide loss in Acinetobacter baumannii

Acinetobacter baumannii can acquire resistance to colistin via complete loss of lipopolysaccharide (LPS) biosynthesis due to mutations in the lpxA, lpxC and lpxD genes. However, although colistin is increasingly being used for the treatment of multidrug resistant infections, very few A. baumannii cl...

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Bibliographic Details
Main Authors: Marta Carretero-Ledesma, Meritxell García-Quintanilla, Reyes Martín-Peña, Marina R. Pulido, Jerónimo Pachón, Michael J. McConnell
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Virulence
Subjects:
Acinetobacter baumannii
colistin
fitness
lipopolysaccharide
virulence
Online Access:http://dx.doi.org/10.1080/21505594.2018.1460187

Internet

http://dx.doi.org/10.1080/21505594.2018.1460187

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